Sybaritic Cougars with Ecosexual Tendencies Good Vibrations Polk, 1620 Polk, SF; (415) 345-0400, www.goodvibes.com. 6 p.m.–8 p.m., free. Sex-positive activists Annie Sprinkle and partner Beth Stephens host a retrospective of their Love Art Lab series.
The Tubesteak Connection Aunt Charlie's, 133 Turk, SF; (415) 441-2922, www.auntcharlieslounge.com. 10 p.m., $4. A sticky, finger-lickin', Hi-NRG hijinks tribute to bathhouse disco and funk rarities, swarthy clones, and outfits Grace Jones would die for. With DJ Bus Station John.
Art Attack Pride Supperclub, 657 Harrison, SF; (415) 348-0900, www.supperclub.com. 9 p.m., $20. Video artist III paints the club fuchsia for DJ Lady Kier of Deee-Lite, the return of drag-rock amazers Pepperspray, and LA mesh-wonder Fade-Dra.
Bearracuda Pride DNA Lounge, 375 11th St., SF; (415) 626-2532, www.dnalounge.com. 9 p.m.-late. $20. Two floors of beard rubs, belly bumps, fur fun, and hairy hijinks as the city's wild bear club goes big. DJ Ted Eiel heads up.
Bibi Gay Middle Eastern Mega Pride Party Paradise, 1501 Folsom, SF; (415) 252-5018, www.paradisesf.com. 9 p.m., $15. One of the most-anticipated parties of the season, with DJs Nile, Nadar, and Cheon delving into global sounds for a hip-shaking, ululating crowd of all stripes. Hookahs! Hotties! Bellydancers!
Folsom Friday Various SoMa venues, www.folsomfriday.com. 10 p.m.–2 a.m., free. Shuttles run down Folsom Street all night for a sleazy-fun bar crawl in SF's other mecca for queer venues, including Truck, Chaps, Powerhouse, Blow Buddies, Lone Star, Mr. S, and Off Ramp Leathers.
MR. Mighty, 119 Utah, SF; (415) 626-7001, www.mighty119.com. 8 p.m.–4 a.m. $15. Break out your giant fake mustaches: NYC's Larry Tee and our own house hero David Harness rock all night at this annual campy hoot. Yes, there'll be a hot 'stache (and 'stache-riding?) contest.
San Francisco Trans March Dolores Park, Dolores and 18th St.; (415) 447-2774, www.transmarch.org. 3 p.m. stage, 7 p.m. march; free. Join the transgender community of San Francisco and beyond for a day of live performances, speeches, and not-so-military marching.
Some Thing Biggest Bestest Gayest Funnest Drag Show Sensation! Ever The Stud, 399 Ninth St., SF; (415) 863-6623, www.studsf.com. 9 p.m.–4 a.m., $10. Er, the name kind of says it all? The packed weekly club goes nuclear. VivvyAnne ForeverMore, Glamamore, Juanita More, Down-E, Diamond Daggers, Anna Conda &ldots; who'll walk away with the mushroom cloud?
Original Plumbing presents Unofficial! Elbo Room, 647 Valencia, SF; (415) 552-7788, www.elbo.com. 9 p.m., $10. A party in honor of trans pride and visibility — plus, it'll be a blast. Rocco Katastrophe and Jenna Riot host, DJs Chelsea Starr and 100 spokes spin, furry photo booth, trans slideshow, performances by Glenn Marla and Ice Cream Socialites.